There is no established role for adjuvant radiation therapy in the management of the resected teratoma. On the other hand, germinomas are highly radiosensitive and radiation therapy is curative in the majority of patients. Subarach-noid dissemination of germinomas is well recognized but, in the absence of dissemination at diagnosis, subarachnoid spread occurs infrequently and the role of cranio-spinal irradiation is controversial.
Malignant non-germinomatous germ cell tumors are much less radiosensitive and the use of radiation therapy as a stand-alone adjuvant modality results in tumor recurrence in the majority of cases. However, combination therapy with radiation and chemotherapy has resulted in long-term disease control in the majority of patients in several recent series .
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.