The only modality that is demonstrated effective for intrinsic brainstem gliomas, albeit transiently, involves field radiation therapy of doses exceeding 50 GY. Use of this modality often results in symptomatic improvement but, in the vast majority of children, progression occurs despite completion of radiation therapy. Radiation therapy for focal brainstem lesions results in a high degree of disease control, which is not surprising given that the majority of these tumors are pilocytic in histology. Radiation therapy can be employed should there be progression after surgical resection or in those instances in which the risk of severe neurologic compromise is sufficiently high from re-operation.
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.