The three main presenting features are similar to pituitary adenomas: endocrine disturbance, headache and visual impairment. In a recent large series of over 28 RCCs , the mean age at presentation was 45 years. Clinically, endocrine disturbance was the most common presentation (50%), including amenorrhea (37.5% of female patients), growth retardation, impotence and DI. Biochemically, hypopitu-itarism, hyperprolactinemia and gonadotrophin deficiencies were the common endocrine findings. Headache was a major feature in 32.1% and visual disturbance in14.3%. Patterns of visual disturbance included central field loss as well as the peripheral field loss expected in sellar region lesions. Four patients had pre-operative DI, a feature that, in the authors' opinion, excludes pituitary adenoma.
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Are Headaches Taking Your Life Hostage and Preventing You From Living to Your Fullest Potential? Are you tired of being given the run around by doctors who tell you that your headaches or migraines are psychological or that they have no cause that can be treated? Are you sick of calling in sick because you woke up with a headache so bad that you can barely think or see straight?