Pfeiffer syndrome was first described in 1964 and has characteristic features of broad thumbs and great toes, partial soft tissue syndactyly of the hands/feet and also craniosynostosis . Other features include maxillary hypoplasia, with a class III malocclusion, hypertelorism, exorbitism, strabismus, downward-slanting palpebral fissures, depressed nasal bridge, beaked nose and turribrachycephaly due to the bilateral coronal synostosis (Fig. 26.3). Additional findings which have been described include fused cervical and lumbar vertebrae and abnormalities of the humerus, pelvis and radioulnar joint, as well as cleft palate.
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.