One report estimates that the enhancing component represents as little as 50% of the total cell burden . The fact that recent studies have been able to show any impact of surgical resection based on extent of removal of contrast-enhancing material suggests that this component of the tumor subserves an important biological function that is independent of tumor burden or volume. Recognizing that gross total resection improves outcome but that these benefits were negated by surgically induced neurological deterioration, Shinoda et al. developed a pre-operative MRI-based grading scheme that incorporates tumor size, location and proximity to eloquent cortex to select candidates suitable for gross total resection .
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.