Fig. 26.3. Pfeiffer syndrome, with maxillary hypoplasia, hypertelorism, exorbitism, downward-slanting palpebral fissures, depressed nasal bridge, beaked nose and turribrachycephaly.

The inheritance pattern is most commonly autosomal-dominant, with complete penetrance and variable expressivity. Sporadic cases have also been reported and tend to be more severe in nature [16,17]. The severity of craniofacial deformity in the usual form of Pfeiffer syndrome is lower than that found in Apert syndrome.

The intelligence is usually normal in Pfeiffer syndrome; however, other CNS abnormalities have been reported, such as seizures, hydro-cephalus and Arnold-Chiari malformations [18]. Sporadic cases of cloverleaf skull have also been reported in association with Pfeiffer syndrome. These cases often have additional anomalies that are not found in the usual form of Pfeiffer syndrome [1].

Cure Your Yeast Infection For Good

Cure Your Yeast Infection For Good

The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.

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