Neuropathology

Fig. 3.3. a Pleomorphic nuclei and cytoplasms (H&E), at first suggesting an anaplastic astrocytoma. bThe CT scan, however, showed multiple lesions that suggested metastatic cancer and prompted the biopsy seen in a. The combination of a and b suggested MS, which was confirmed by the sharp-edged demyelination in c, the upper right triangular portion being blue in the original (LFB-PAS-H), even though the astrocytes were quite pleomorphic in d (NP8667, Holzer's crystal violet for astrocytes).

Fig. 3.3. a Pleomorphic nuclei and cytoplasms (H&E), at first suggesting an anaplastic astrocytoma. bThe CT scan, however, showed multiple lesions that suggested metastatic cancer and prompted the biopsy seen in a. The combination of a and b suggested MS, which was confirmed by the sharp-edged demyelination in c, the upper right triangular portion being blue in the original (LFB-PAS-H), even though the astrocytes were quite pleomorphic in d (NP8667, Holzer's crystal violet for astrocytes).

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