Craniosynostosis results from the premature fusion of one or more cranial sutures. This untimely fusion produces progressive and characteristic craniofacial abnormalities. The etiology may be either sporadic (of non-syndromic nature) or secondary to a distinct syndrome. Recent advances in molecular biology and genetics provide clues as to the possible causes of this disorder. Craniosynostosis is diagnosed clinically and confirmed with radiographic and other studies. Although predominantly a problem of cosmesis, craniosynostosis may also be complicated by neurological dysfunction.
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.