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Asymptomatic lesions discovered in the course of staging patients with known systemic cancer.

Asymptomatic lesions discovered in the course of staging patients with known systemic cancer.

Adapted from Posner JB. Brain metastases: 1995. A brief review. J Neuro-oncol 1996;27:287-93.

generalized, are the presenting symptom in about 10% of patients. They, too, are more frequent in patients with multiple metastases [3]. Hemorrhage or infarction from a tumor embolus occurs in 5-10% of cases [3]. Hemorrhage is more common with metastases from melanoma, choriocarcinoma, renal cell carcinoma and bronchogenic carcinoma.

The differential diagnosis of the clinical presentation of metastasis includes other mass lesions (abscess, granuloma, resolving hematoma, radiation necrosis) demyelination and infarction (non-bacterial thrombotic endocarditis, cerebral venous occlusion) [4].

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