normo- or hypocapnia) Decrease in CMRO2 Decrease in CBF

Decrease in ICP

Isoelectric EEG with high doses of anticonvulsant

Myocardial depression (potential for circulatory collapse in hypovolemia or with high doses) Enhanced seizure focus activity (methohexitone)

Isopropyl phenol

Appropriate for total intravenous anesthesia (TIVA) and prolonged sedation

Decrease in CMRO2 Decrease in CBF

Decrease in ICP

Hypotension due to vasodilatation and cardiac depression (may compromise CPP)




Active metabolites (prolonged action in

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Anxiety and Panic Attacks

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