Epidemiology

The birth prevalence of craniosynostosis is estimated at 343-476 per 1,000,000 live births (i.e. affecting 1 in 2,100 to 1 in 2,900 newborns) [20, 21]. Non-syndromic craniosynostosis represents the most prevalent form. Involvement of the sagittal suture is the most common form and accounts for between 40 and 60% of cases. This is followed by coronal synostosis, which occurs in approximately 20-30% of cases. Unilateral coronal synostosis outnumbers bilateral involvement by a 2:1 margin. Metopic craniosynostosis is estimated to comprise less than 10% of cases and true lambdoid craniosynostosis is much rarer [20]. Two or more sutures may be involved in 4-8% of non-syndromic cran-iosynostosis.

Syndromic craniosynostosis is much less common, although new syndromes are becoming increasingly recognized. Syndromic cran-iosynostoses typically involve multiple sutures. There are more than 90 syndromes characterized by craniosynostosis and various associated anomalies [20]. The birth prevalence of the two more common syndromes - Apert and Crouzon - are estimated at 13.7-15.5 per 1,000,000 [22] and 15.5-16.5 per 1,000,000 [22], respectively.

Cure Your Yeast Infection For Good

Cure Your Yeast Infection For Good

The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.

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