A patient cured of their disease will become dependent on cortisol replacement. If hydrocortisone is not given during the procedure, the cortisol level can be checked the following day, about 24 hours later. If the surgery is successful, cortisol levels will have fallen to below 50, but replacement must start immediately. Surgical failure warrants prompt re-exploration, particularly if an adenoma was found at the first exploration. Most experienced authors in large series report a cure rate of better than 70%. Failed surgical treatment of Cushing's disease requires radiotherapy. Currently, the fashion for bilateral adrenalectomy may be waning in favor of controlling the cortisol hypersecretion with ketoconazole.
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.