Cerebral lymphoma, specifically PCNSL, is increasing in incidence. The role of surgery is usually limited to stereotactic biopsy for diagnosis. Multimodality therapy, combining chemotherapy and whole-brain radiotherapy, has improved the survival of patients with primary CNS lymphoma, but long-term relapse-free survival is still rare. Currently, a number of clinical trials are evaluating single-modality treatment protocols, in an effort to lengthen patient survival without incurring late neurologic toxicity.
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.