Acromegaly

Reduction of growth hormone levels results in an early cessation of sweating. Diabetes mellitus becomes easier to control and many patients can be managed on diet or oral hypoglycemic alone. On the second day, it is useful to carry out a glucose tolerance test with GH levels (i.e. before discharge). GH will fall to below 2 mlU/l, and ideally below 0.5 mlU/l if cured. If the patient is not "cured", early re-exploration is often worthwhile.

Expected cure rates vary between 60% and 80%. If surgery fails, the patient will need to have GH hypersecretion controlled by somato-statin analogues and undergo pituitary irradiation.

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