1. Remove the foster mother from her pups.

2. Mix the foster pups with the natural pups.

3. Try to make the foster mother urinate on the mixed litter. The animal will often urinate on being picked up and restrained with one hand. SD rats will often foster pups without this stimulus.

4. Leave the mother undisturbed with the mixed litter for at least 3 h.

5. Remove some of the natural pups to leave a litter of 12. The mother will be unable to care for a larger litter.

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