FIGURE 21.31 Relatedness of DNA by Filter Hybridization

(A) DNA No. 1 is denatured and attached to a filter. (B) When DNA No. 2 is added to the filter, some of the DNA strands will hybridize, provided that the sequences are similar enough. If the sequence is identical, all of the single-stranded red DNA should hybridize to strands of green DNA. If the sequences are very different, little or none of the green DNA will hybridize with the red.

Hybridization occurs on filter
Some pass through

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