Newly formed stop codon mRNA
Several proteins of the mammalian nervous system undergo A to I editing in the coding sequence of their mRNAs.
The guide RNA base pairs along a specific region of the trypanosome mRNA. The extra adenine (A) of the AGA sequence in the guide RNA is used as a template to insert uracil (U) into the mRNA. (Note: some slightly distorted duplex RNA structures allow guanine, as in the AGA sequence shown, to pair with uracil.)
^ Guide RNA
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