Replication Forks

Additional cuts

FIGURE 15.09 Replicative and Conservative Transposition are Related

Both conservative and replicative transpositions begin with single-stranded cuts and the joining of ends. In conservative transposition (right side) a second cut completely releases the transposon from the donor molecule after the donor and recipient molecule have joined. In contrast, in replicative transposition, the transposon splits into two single-stranded copies at this stage. Next the host cell fills in the single-stranded gaps, which is just the short target sequence in conservative replication, but the entire transposon in replicative transposition.


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