Introduction to Genomics

DNA Sequencing—General Principle

The Chain Termination Method for Sequencing DNA

DNA Polymerases for Sequencing DNA

Producing Template DNA for Sequencing

Primer Walking along a Strand of DNA

Automated Sequencing

The Emergence of DNA Chip Technology

The Oligonucleotide Array Detector


Nanopore Detectors for DNA

Large Scale Mapping with Sequence Tags

Mapping of Sequence Tagged Sites

Assembling Small Genomes by Shotgun Sequencing

Race for the Human Genome

Assembling a Genome from Large Cloned Contigs

Assembling a Genome by Directed Shotgun Sequencing

Survey of the Human Genome

Sequence Polymorphisms: SSLPs and SNPs

Gene Identification by Exon Trapping

Bioinformatics and Computer Analysis

A second major revision and analysis of the human genome announced in 2004 has reduced the estimated number of human genes from 35,000 to 25,000.

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