Ch
MutS
MutS
MutH MutH
MutL
MutH MutH
One of MutH subunits binds to methyl group and
DNA in between loops out
MutS is still bound to G/T mismatch
MutS
MutH MutH
MutL
One of MutH subunits binds to methyl group and
DNA in between loops out
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