B

Oxidized

DNA binding site

DNA binding site

FIGURE 9.19 Regulatory Proteins That Respond to Oxidation or Reduction

A) OxyR changes from the DNA-binding disulfide form to the inactive sulfhydryl form. B) The reduced state of Fnr actively binds DNA, whereas the oxidized state is inactive. Note that the disassembled form of the protein is inactive in both instances.

Reduced

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