FIGURE 9.18 Sequestration of Mlc by PtsG Protein
A) The membrane transporter PtsG has an open channel for glucose when it is phosphor ylated (P).
B) Glucose enters the cell and is converted into glucose-6-phosphate so removing the phosphate.
C) The dephosphorylated PtsG protein binds the Mlc repressor. This inactivates the Mlc repressor as it can no longer bind DNA when trapped by PtsG. If the supply of glucose runs out, PtsG will be able to retain its phosphate and Mlc is released.
Mlc Active repressor
Was this article helpful?