Residual And Recurrent Tumour

Residual tumour is defined as tumour which persists after initial treatment. It is diagnosed clinically by nonregression of the tumour mass and radiologically by a persisting tumour mass, incomplete restoration of organ zonal anatomy or nondevelopment of expected treatment effects.

Tumour recurrence is locoregional tumour detected more than 6 months after initial therapy when there has been a documented treatment response. Recurrence can be diagnosed clinically by physical examination or rising biochemical tumour markers. It may be diagnosed radiologically by the identification of a new mass, increasing size of an existing mass or new abnormal signal intensity within an organ. Infiltrative recurrence may be difficult to detect and relies upon the identification of more subtle changes such as thickening of fascial planes.

When residual or recurrent tumour is detected, biopsy confirmation should be obtained before further treatment is started. For pelvic cancers the treatment given to the patient with residual or recurrent disease depends on the primary tumour site and type, the previous therapy received, and the current clinical findings. In this situation, pelvic clearance should be considered.

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