Toward Nanotube Membranes for Biochemical Sensors

Many of the principles of biochemical sensing with nanotube membranes are inspired by the results obtained with separations using such membranes. The small, often molecular, sizes of the nanotubes prepared offer new approaches to bioanalytical chemistry at the nanometer scale. We have previously described composite membranes with thin polymer skins that function as chemical sensors. In this chapter, we will discuss our results with nanotube membranes that function as ion channel mimics. These experiments are our first step toward constructing nanotube-based biochemical sensors that function in a manner analogous to biological channels.

9.5.1 Ligand-Gated Membranes


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