TNF Blockade

TNF-a is a pro-inflammatory cytokine that mediates both inflammatory synovitis and breakdown of articular cartilage. It also induces the production of other cytokines and matrix metalloproteinases that are important within the rheumatoid joint (77). TNF-a binds to either of the two cellular receptors, p55 or p75, which also exist in soluble shortened forms in different body fluids. These receptors are thought to be involved in the regulation of TNF-a activity (78). Currently three TNF blockers, infliximab, etanercept, and adalimumab are available for use in clinical practice.

Cure Your Yeast Infection For Good

Cure Your Yeast Infection For Good

The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.

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