In mammalian cells, tubulin is a structurally heterogeneous 100-kDa «13 heterodimer with six a- and seven 1-tubulin isotypes. The antimitotics used in chemotherapy, including taxanes and vinca alkaloids, primarily target 1-I tubulin. Paclitaxel is the prototype of the taxane family of antitumor drugs, which also includes docetaxel. It was the first natural product shown to induce the formation of microtubule bundles in cells, followed by impairment of depolymerization and apoptosis by aberrant mitosis or a multinucleated

Dealing With Asthma Naturally

Dealing With Asthma Naturally

Do You Suffer From ASTHMA Chronic asthma is a paralyzing, suffocating and socially isolating condition that can cause anxiety that can trigger even more attacks. Before you know it you are caught in a vicious cycle Put an end to the dependence on inhalers, buying expensive prescription drugs and avoidance of allergenic situations and animals. Get control of your life again and Deal With Asthma Naturally

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