Serotonin Transporter

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Selective serotonin reuptake inhibitors (SSRIs) are widely used for the treatment of depression because of their efficacy and relatively favorable side-effect profile compared with those of the tricyclic antidepressants. SSRIs act by interfering with the activity of the serotonin transporter (SERT) (49). A number of polymorphisms have been reported in the SERT gene (50-52), and genetic variations in the SERT promoter have been linked to altered functions, such as the association between the short (S) allele (44 bp deletion) of the SERT-PR site and poor response to fluvoxamine and paroxetine in patients treated for major depression (53,54).

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Defeat Depression

Defeat Depression

Learning About How To Defeat Depression Can Have Amazing Benefits For Your Life And Success! Discover ways to cope with depression and melancholic tendencies! Depression and anxiety particularly have become so prevalent that it’s exceedingly common for individuals to be taking medication for one or even both of these mood disorders.

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