Diabetes mellitus (DM), hyperlipidemia, and osteoporosis are common diseases, responsible, directly and indirectly, for significant morbidity and mortality worldwide. Each condition presents a variety of very specific management problems, but they are unified by a common theme—they are frequently asymptomatic and often manifest through their complications. This chapter focuses on the current level of understanding and the role of pharmacogenetics in the management of these three metabolic diseases. The influence of genes on the pharmacokinetics of the currently available drugs is discussed, and the interaction between genes and the environment in pathophysiology, including the response to drug therapy, is also considered.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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