Cyp2c9

Three defective alleles have been reported in the CYP2C9 enzyme, two of which confer decreased activity. Their frequency ranges from 1% to13% in different populations (13-15). Substrates of CYP2C9 include nonsteroidal anti-inflammatory drugs and hypoglycemic agents (13-15). The clinical relevance of CYP2C9 is particularly noticed in the metabolism of drugs that are used to treat Type II diabetes, wherein decreased clearance of these drugs may result in severe hypoglycemia. Another relevant example is S-warfarin, where major bleeding may occur (10).

Cure Your Yeast Infection For Good

Cure Your Yeast Infection For Good

The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.

Get My Free Ebook


Post a comment