MR Lymphangiography Technique

Anuradha Saokar and Mukesh Harisinghani

Division of Abdominal Imaging and Interventional Radiology, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, U.S.A.

Jelle Barentsz

Department of Radiology, Radboud University Medical Center Nijimegen, Nijimegen, The Netherlands

A Note from the Editors rhe detection of metastases to lymph nodes is clinically important in the evaluation of virtually any type of primary tumor. Radiologists recognize the limitations of current morphological imaging techniques. Magnetic resonance (MR) lymphography using the intravenously administered contrast agent ferumoxtran-10 has emerged as a powerful new tool for the evaluation of nodal involvement. Much research attesting to its accuracy for nodal detection and characterization (including the detection of micrometastases) appears in the literature, although efficacy data related to changing patient management and altering clinical outcomes are generally lacking. The authors of this chapter are pioneers in the clinical evaluation of MR lymphography and herein discuss advanced aspects with an emphasis on the optimization of acquisition strategies.

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