Adrenal Lesions

On survey of the literature,18FDG PET was used to distinguish between malignant and benign adrenal lesions in four studies with a total of 161 lesions in 142 patients. There were 55 true positive results, 47 true negative results, four false positive results, and no false negative results (12-15). In the prospective study of 33 adrenal masses in 27 patients with proven lung cancer FDG PET had a sensitivity of 100% and a specificity of 80% (15). Recently promising results have been obtained when chemical shift MRI

has been used to characterize adrenal lesions on the basis of their fat content. There are currently no studies available which compare FDG PET to chemical shift MR.

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