Finally, it is relevant to comment on Mathematica and how it relates to this book: we make extensive use of Mathematica in this book; in fact, it has been typeset in this program. Even in Chapter 1 there are examples of quite sophisticated usage of Mathematica. Therefore, it is recommended that the CD version of the book be read on your computer with Mathematica available to run the various examples and exercises.

As noted above, the main concepts of biochemical kinetics and metabolic control analysis are illustrated in the worked examples (marked with a Q) and are expanded upon in the exercises that are located at the conclusion of each chapter, all using Mathematica in some way. We encourage you to not only reproduce the output of these examples but to make modifications to the programs and explore the results of these changes. A spin-off of all the biochemical, metabolic, and kinetic investigations will be the development of a facility in the use of this truly outstanding program.

If, on occasion, a Mathematica function is encountered that requires further clarification, simply proceed to the Help Menu and look up the index. Alternatively, a hard copy of the Mathematica book can be used, but after some practice you will most likely find the screen version to be more convenient.

The easy-to-use text by DonĀ® is a valuable source of descriptions of the various functions and semantics of Mathematica and for illustrating their usage. There are also many specialized texts, like the present one, that use Mathematica to present their particular scientific or mathematical themes and that can provide examples and tricks of usage that are seemingly infinite in number. We anticipate that it will become obvious to you that scientists have gained, in Mathematica, access to mathematical 'power' and resources that were undreamed of even 5 years ago.

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