Tumor Specific Effects

Alteration of physiologic function or distortion of normal anatomy may occur due to specific tumor effects. For example, tumors of the mediastinum or neck may cause venous congestion, superior vena cava obstruction, airway compression, or tracheal deviation that may make establishment of an airway or ventilatory management difficult. Gastrointestinal tumors may cause obstruction, causing an aspiration risk. Cerebral tumors or brain metastases can cause changes in mental status, syndrome of inappropriate secretion of antidi-uretic hormone making perioperative fluid management difficult, or may cause an increased intercerebral pressure that affects anesthesia management of the patient.

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