Targeted Therapy

Historically, cancers have been treated with nonspecific geno-toxic agents and antimitotic drugs such as cisplatin and taxol. Such chemotherapeutic agents are successful in killing cancerous cells; however, their lack of specificity can result in increased toxicity for normal cells as well. Knowing the pathways required for the transformation of human cells allows not only the rational design of drugs against specific pathways in cancer, but also the correct application of treatment based on the mutations present in individual tumors. In particular, the pRb pathway and Ras pathway have been examined for potential small molecule drugs that are effective and easily delivered. Both these pathways contain enzymes that catalyze posttranslation modifications required for functional activity, and these enzymes are particularly important for small molecule inhibitor approaches.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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