1. Regaud C. Sur Les Principles Radiophysiologiques De La Radiotherapie Des Cancers. Acta Radiol 1930;86:456-461.

2. Coutard H. Roentgen therapy of epitheliomas of the tonsillar region, hypopharynx and larynx from 1920 to 1926. Am J Roentgenol 1992;8:313-319.

3. Coutard H. Present conception of treatment of the larynx. Radiology 1940;34:136-145.

4. Ward JF. Mechanisms of DNA repair and their potential modification for radiotherapy. Int J Radiat Oncol Biol Phys 1986; 12:1027-1032.

5. Haber JE. Partners and pathways repairing a double-strand break. Trends Genet 2000;16:259-264.

6. Cohen-Jonathan E, Bernhard E, McKenna GW. How does radiation kill? Curr Opin Chem Biol 1999;3:77-83.

7. Steel GG (ed). Clonogenic Cells and the Concept of Cell Survival in Basic Clinical Radiobiology. London: Arnold, 2002:52-54.

8. Cox JD. Proton beam radiation therapy in treatment of cancer. Clin Adv Hematol Oncol 2993;2:355-356.

9. Jagsi R, Delaney TF, Donelan K, Tarbell NJ. Real time rationing of scarce resources: the Northeast Proton Therapy Center experience. J Clin Oncol 2004;22:2246-2250.

10. Cline SD, Hanawalt PC. Who's on first in the cellular response to DNA damage? Nat Rev 2003;4:361-372.

11. Lindahl T, Wood RD. Quality control by DNA repair. Science 1000;286:1897-1905.

12. Caldecott KW. XRCC1 and DNA strand break repair. DNA Repair 2003;2:955-969.

13. Radivoyevitch T, Taverna P, Schupp JE, Kinsella TJ. The linear-quadratic log-survival radiation dose model: confidence ellipses, drug-drug interactions, and brachytherapeutic gains. Med Hypotheses Res 2004;1:23-28.

14. Valerie K, Povirk LF. Regulation and mechanisms of mammalian double-strand break repair. Oncogene 2003;22:5792-5812.

15. Leskov KS, Criswell T, Antonio S, Yang C-R, Kinsella TJ, Boothman DA. When x-ray inducible proteins meet DNA double strand break repair. Semin Radiat Oncol 2001;11: 352-372.

16. Lee SE, Mitchell RA, Cheng A, et al. Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways as a function of the cell cycle. Mol Cell Biol 1997; 17:1425-1433.

17. Thompson LH. Evidence that mammalian cells possess homologous recombinational repair pathways. Mutat Res 1996;363:77-88.

18. Vandyck E, Stasiak AZ, Stasiak A, et al. Binding of double-strand breaks in DNA by human Rad 52 protein. Nature (Lond) 1999; 398:728-731.

19. Pawlik TM, Keyomarsi K. Role of cell cycle in mediating sensitivity to radiotherapy. Int J Radiat Oncol Biol Phys 2004;59: 928-942.

20. Sinclar W, Morton R. X-ray and ultraviolet sensitivity of synchronized Chinese hamster cells in culture. Nature (Lond) 1965;199:1158-1160.

21. Malumbres M, Baracid M. To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer 2001;1:222-231.

22. Nagasawa H, Li CY, Maki CG, et al. Relationship between radiation-induced G1 phase arrest and p53 function in human tumor cells. Cancer Res 1995;55:1842-1846.

23. Giaccia AJ, Kastan MB. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev 1998; 12:2973-2983.

24. Sherr CJ. The Pezcoller Lecture: Cancer cell cycles revisited. Cancer Res 2000;60:3689-3695.

25. Xu B, Kim SY, Lim DS, et al. Two molecularly distinct G(2)/M checkpoints are induced by ionizing radiation. Mol Cell Biol 2002;22:1049-1059.

26. Yamane K, Chen J, Kinsella TJ. Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2/M cell cycle checkpoint. Cancer Res 2003;63:3049-3053.

27. Yan T, Schupp JE, Hwang H-S, et al. Loss of DNA mismatch repair imparts defective cdc2 signaling and G2 arrest responses without altering survival after ionizing radiation. Cancer Res 2001;61:8290-8297.

28. Chao DT, Korsmeyer SJ. BCL-2 family: regulators of cell death. Annu Rev Immunol 1998;16:395-419.

29. Reed JC. Dysregulation of apoptosis in cancer. J Clin Oncol 1999;117:2941-2953.

30. Levin AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-331.

31. Thomlinson R, Gray L. The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer 1955;9:539-544.

32. Brown JM. Evidence for acutely hypoxic cells in mouse tumours and a possible mechanism for reoxygenation. Br J Radiol 1979; 52:650-658.

33. Raleigh J, Dewhirst M, Thrall D. Measuring tumor hypoxia. Semin Radiat Oncol 1996;6:37-46.

34. Chaplin D, Olive P, Durand R. Intermittent blood flow in a murine tumor: radiobiological effects. Cancer Res 1987; 47:597-604.

35. Vaupel P. Tumor microenvironmental physiology and its implications for radiation oncology. Semin Radiat Oncol 2004;14:198-206.

36. Kaanders J, Bussink J, van der Kogel AJ. Clinical studies of hypoxia modification in radiotherapy. Semin Radiat Oncol 2004;14:233-240.

37. Kaanders J, Wijffels KI, Marres , et al. Pomonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer. Cancer Res 2002;62:7066-7074.

38. Harris AL. Hypoxia—a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.

39. Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003;3:721-732.

40. Purdy JA. Defining our goals: volume and dose specification for 3-D conformal radiation therapy. In: Meyer JL, Purdy JA (eds). Frontiers of Radiation Therapy and Oncology. 3-D Conformal Radiotherapy: A New Era in the Irradiation of Cancer. Basel: Karger, 1996:24-30.

41. Prescribing, Recording, and Reporting Photon Beam Therapy. International Commission on Radiation Units and Measurements (ICRU) Report 50, Bethesda, MD: ICRU Publications; 1993.

42. Prescribing, Recording, and Reporting Photon Beam Therapy. International Commission on Radiation Units and Measurements (ICRU) Report 62 (Supplement to ICRU Report 50), Bethesda, MD: ICRU Publications; 1999.

43. Purdy JA. Dose-volume specification: new challenges with intensity-modulated radiation therapy. Semin Radiat Oncol 2002;12:199-209.

44. Low DA. Quality assurance of intensity-modulated radiotherapy. Semin Radiat Oncol 2002;12:219-228.

45. Falco T, Shenouda G, Kaufman C, et al. Ultrasound imaging for external-beam prostate treatment setup and dosimetric verification. Med Dosim 2000;27:271-273.

46. Zelefsky MJ, Fuks Z, Leibel SA. Intensity-modulated radiation therapy for prostate cancer. Sem Radiat Oncol 2002;12:229-237.

47. Eisbruch A, Foote RL, O'Sullivan B, Beitler J, Vikram B. Intensity-modulated radiation therapy for head and neck cancer: emphasis on the selection and delineation of the targets. Semin Radiat Oncol 2002;12:238-249s.

48. Ling CC, Mitchell JB. Functional imaging and its application to radiation oncology. Semin Radiat Oncol 2001;11:1-92.

49. Knox SJ, Meredith RF. Clinical radioimmunotherapy. Semin Radiat Oncol 2000;10:73-93.

50. McDougall IR. Systemic radiation therapy with unsealed radionuclides. Semin Radiat Oncol 2000;10:94-102.

51. Houshmand P, Zlotnik A. Targetng tumor cells. Curr Opin Cell Biol 2003;15:640-644.

52. Hu KS, Enker WE, Harrison LB. High-dose rate intraoperative irradiation: current status and future directions. Semin Radiat Oncol 2002;12:62-80.

53. Blasko JC, Mate T, Sylvester JE, Grimm PD, Cavanaugh W. Brachytherapy for carcinoma of the prostate: techniques, patient selection and clinical outcomes. Semin Radiat Oncol 2002; 12:81-94.

54. Beaulieu L, Archambault L, Aubin S, et al. The robustness of dose distributions to displacement and migration of I-125 permanent seed implants over a wide range of seed number, activity, and designs. Int J Radiat Oncol Biol Phys 2004;58: 1298-1308.

55. Nguyen HP, Kaluza GL, Zymek PT, et al. Intracoronary brachytherapy. Catheter Cardiovasc Interv 2002;56:281-288.

56. Wang R, Li XA. Dosimetric comparison of two Sr-90/Y-90 sources for intravascular brachytherapy: an EGSnrc Monte Carlo calculation. Phys Med Biol 2002;47:4259-4269.

57. Streeter OE, Vicini FA, Keisch M, et al. MammoSite radiation therapy system. Breast 2003;12:491-496.

58. Keisch M, Vicini F, Kuske RR, et al. Initial clinical experience with the MammoSite breast brachytherapy applicator in women with early-stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys 2003;55:289-293.

59. Merrick HW, Dobelbower RR. Intraoperative radiation therapy in surgical oncology. Surg Oncol Clin N Am 2003;12:883-899.

60. Biggs PJ, Noyes RD, Willett CG. Clinical physics, applicator choice, technique, and equipment for electron intraoperative radiation therapy. Surg Oncol Clin N Am 2003;12:899-924.

61. Sindelar WF, Kinsella TJ. Normal tissue tolerance to intraoperative radiotherapy. Surg Oncol Clin N Am 2003;12:925-942.

62. Merrick HW, Thomas CR (eds). Intraoperative radiotherapy. Surg Oncol Clin N Am 2003;12:955-1078.

63. Sneed PK, Sun JN, Goetsch SJ, et al. A multi-institutional review of radiosurgery alone versus radiosurgery with whole brain radiotherapy as the initial management of brain metastases. Int J Radiat Oncol Biol Phys 2002;53:519-526.

64. Lorenzoni J, Deuriendt D, Massager N, et al. Radiosurgery for treatment of brain metastases: estimation of patient eligibility using three stratification systems. Int J Radiat Oncol Biol Phys 2004;60:218-224.

65. McGinn CJ, Lawrence TS. Recent advances in the use of radiosensitizing nucleosides. Semin Radiat Oncol 2001;11:270-280.

66. Lawrence TS, Blackstock G, McGinn CJ. The mechanisms of action of radiosensitization of conventional chemotherapeutic agents. Semin Radiat Oncol 2003;13:13-21.

67. Vallerga AK, Zarling D, Kinsella TJ. New radiosensitizing regimens, drugs, prodrugs and candidates: Capecitabine, Gem-citabine, Fludarabine, IPdR, Avastin, Veglin, Gleevac, Radvac, Erbitux or Iressa. Clin Adv Hematol Oncol 2004;2: 793-805.

68. Hwang H-S, Davis TW, Houghton JA, Kinsella TJ. Radiosensi-tivity of thymidylate synthase deficient human colon cancer cells is affected by progression through the G1 restriction point into S-phase: implications for fluoropyrimidine radiosensitiza-tion. Cancer Res 2000;60:92-100.

69. Kuo M-L, Kinsella TJ. Expression of ribonucleotide reductase following ionizing radiation in human cervical carcinoma cells. Cancer Res 1998;58:2245-2252.

70. Kuo M-L, Hwang H-S, Sosnay PR, Kunugi KA, Kinsella TJ. Overexpression of the R2 subunit of ribonucleotide reductase in human nasopharyngeal cancer cells reduces radiosensitivity. Cancer J (Boston) 2003;9:277-285.

71. Wouters BG, Weppler SA, Koritzinsky M, et al. Hypoxia as a target for combined modality treatments. Eur J Cancer 2002; 38:240-257.

72. Stratford IJ, Williams KJ, Cowen RL, Jaffar M. Combining biore-ductive drugs and radiation for the treatment of solid tumors. Semin Radiat Oncol 2003;13:42-52.

73. Overgaard J, Hansen HS, Overgaard M, et al. A randomized double-blind phase III study of nimorazole as a hypoxic radiosen-sitized in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study Protocol 5-85. Radio-ther Oncol 1998;46:135-146.

74. Sartor CI. Epidermal growth factor family receptors and inhibitors: radiation response modulators. Semin Radiat Oncol 2003; 13:22-30.

75. Siemann DW, Shi W. Targeting the tumor blood vessel network to enhance the efficacy of radiation therapy. Semin Radiat Oncol 2003;13:53-61.

76. Bonner JA, Trigo J, Humblet Y, et al. Phase 3 trial of radiation therapy plus cetuximab versus radiation therapy alone in locally advanced squamous cell carcinomas of the head and neck. Proc ASCO 2004;23:487.

77. Milas L. Cyclooxygenase-2 (COX-2) enzyme inhibitors as potential enhancers of tumor radioresponse. Semin Radiat Oncol 2001;11:290-299.

78. McKenna WG, Muschell RJ, Gupta AK, Hahn SM, Bernhard EJ. Farinesyltransferase inhibitors as radiation sensitizers. Semin Radiat Oncol 2002;12(suppl 2):27-32.

79. Jung M, Dritschilp A. NF-kß signaling pathway as a target for human tumor radiosensitization. Semin Radiat Oncol 2001; 11:346-351.

80. Karran P. Mechanisms of tolerance to DNA damaging therapeutic drugs. Carcinogenesis (Oxf) 2001;22:1921-1937.

81. Yan T, Schupp JE, Hwang H-S, et al. Loss of DNA mismatch repair imparts defective cdc2 signaling and G2 arrest responses without altering survival after ionizing radiation. Cancer Res 2001;61:8290-8297.

82. Berry SE, Kinsella TJ. Targeting DNA mismatch repair for radiosensitization. Semin Radiat Oncol 2001; 11:300315.

83. Seo Y, Yan T, Schupp JE, Kinsella TJ. Differential radiosensitization in DNA mismatch repair proficient and deficient human colon cancer xenografts with 5-iodo-pyrimidinone-2'-deoxyri-bose. Clin Cancer Res 2004;10:7520-7528.

84. Russell JS, Brady K, Burgan WE, et al. Gleevac-mediated inhibition of RAD51 expression and enhancement of tumor cell radiosensitivity. Cancer Res 2003;63:7377-7383.

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