Info

8/43 (19)

8/867 (0.9)e

Kaplan 200129

1,862

102 (5.5)

6/91 (6.6)

6/1,862 (0.3)

Kolb 200230

13,547g

358 (2.6)

37/358 (10)

37/13,547 (0.27)g

Crystal 200332

1,517

38 (2.5)h

7/38 (18)

7/1,517 (0.46)h

Leconte 200331

4,236'

NSf

16/NS

16/4,236 (0.38)

Overall

42,838

1,182/38,602 (3.1)

134/1,171 (11.4)

150/42,838 (0.35)

aBiopsies or aspirations prompted by screening sonography.

b Refers to cancers seen only on breast sonography, expressed as percent of biopsies (PPV).

aBiopsies or aspirations prompted by screening sonography.

b Refers to cancers seen only on breast sonography, expressed as percent of biopsies (PPV).

cAll women had clinical or mammographic abnormalities. Diagnosis was by fine-needle aspiration biopsy. Numbers refer to solid masses. Sixteen cancers were found in 15 women with ipsilateral cancer.

d In this series, 867 women were evaluated because of palpable or mammographic abnormalities; 5 cancers seen only on sonography were in patients with another mammographically or clinically evident cancer.

eCancer was found only on sonography in 0.54% of women with a personal history of cancer compared to 0.26% of women with no personal history of cancer.

f NS, not stated.

gIncludes patients described in 1998 series.9 Number of studies, not women, as some women had more than one study. Cancer was found only on sonography in 0.48% of high-risk women compared to 0.16% of normal risk women.

hCancer was found only on sonography in 4/318 (1.3%) women with first-degree family history or personal history of breast cancer and 3/1,199 (0.25%) women of average risk; biopsies includes 17 aspirations of which 13 yielded clear fluid.

i 1,016 had a personal history of breast cancer and 136 a palpable lesion (with the palpable lesions themselves excluded), although the number of cancers seen in women at high risk was not specified. Sixteen cancers were identified, but the number of biopsies induced by sonography was not specified: results of this study were not included in calculating the biopsy rate or the malignancy rate of biopsies.

Source: Adapted from Reference 26, with permission.

TABLE 28.2. Rates of detection of cancer by magnetic resonance imaging (MRI) only in women at high risk of breast cancer.

Cancers on No. of

MRI only DCIS only MRI +

TABLE 28.2. Rates of detection of cancer by magnetic resonance imaging (MRI) only in women at high risk of breast cancer.

Cancers on No. of

MRI only DCIS only MRI +

Investigator

Mean age (years)

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