Info

250/500mg25

250/500mg24

Erlotinib36

Response rate

18/19%

12/9%

11%

1 year Survival

35/30%

29/24%

?

Median survival

7.6/8.1 months

6.1/6.0 months

?

TABLE 5.4. Phase III trials of gefitinib with chemotherapy as first-line treatment of NSCLC.

INTACT 126

Gem/Cis alone

Chemo + Gefitinib 250mg

Chemo + Gefitinib 500mg

Response rate

44.8%

50.3%

49.7%

1-year survival

44%

41%

43%

Median survival

10.9 months

9.9 months

9.9 months

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