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Superscript numbers are references to support these mechanisms.

Superscript numbers are references to support these mechanisms.

and keratinocyte growth factor (KGF), known growth factors for mesothelial cells, have been detected in pleural lavage fluids in rodents exposed to asbestos.124 The HGF receptor, c-Met, a proto-oncogene product whose activation leads to cell growth and altered morphogenesis, is activated in SV-40-positive human mesothelioma cells.125 High expression levels of c-met have been detected in rat mesothelioma cells and are fra-1 dependent.126

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