for 5 years



Royal Marsden Hospital Tamoxifen Chemoprevention Trial


Randomized Trial

Tamoxifen (20mg) up to 8 years

No differences in the tamoxifen and placebo groups


Multiple Outcomes of


Randomized Trial

Raloxifene (60mg)

65% reduction in risk of both in situ

A Disquistion On The Evils Of Using Tobacco

A Disquistion On The Evils Of Using Tobacco

Among the evils which a vitiated appetite has fastened upon mankind, those that arise from the use of Tobacco hold a prominent place, and call loudly for reform. We pity the poor Chinese, who stupifies body and mind with opium, and the wretched Hindoo, who is under a similar slavery to his favorite plant, the Betel but we present the humiliating spectacle of an enlightened and christian nation, wasting annually more than twenty-five millions of dollars, and destroying the health and the lives of thousands, by a practice not at all less degrading than that of the Chinese or Hindoo.

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