10% among cases; 30% among controls.

80% for round 1; ? 20% for round 2; 16% for round 3; 28% for round 6.

2.7% among cases; 10.1% among deceased controls.

For cancer of rectum and distal colon: adjusted OR = 0.41 (95% CI, 0.25-0.69) For cancer of rest of colon (out of reach of sigmoidoscope): adjusted OR = 0.96 (95% CI, 0.61-1.50)

50% reduction in mortality with FOBT + sigmoidoscopy compared with sigmoidoscopy alone

OR = 0.44 (95% CI, 0.36-0.53) (for any colorectal procedure)

Landmark case-control study that raised possibility of mortality reduction through use of sigmoidoscopy.

Reduction in risk appeared to be limited to rectum and distal colon.


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