Primary colonic GISTs are much less common than gastric, small bowel, and anorectal GISTs. These transmural tumors may involve the intraluminal and extraserosal surfaces of the colon.15 They are smooth or multinodular in contour with areas of low attenuation due to hemorrhage, necrosis, or cystic degeneration. Circumferential involvement of the colon with aneurysmal dilatation of the involved segment of the colon has been described.15

At CT, small lesions are confined to the wall of the colon and appear as mural or submucosal masses, which may ulcerate. Differential diagnosis includes adenocarcinoma, lymphoma, leiomyosarcoma, and metastatic melanoma. Tumors arising adjacent to the colon, such as retroperitoneal sarcomas, may involve the colon and may be mistaken for GISTs.

A Disquistion On The Evils Of Using Tobacco

A Disquistion On The Evils Of Using Tobacco

Among the evils which a vitiated appetite has fastened upon mankind, those that arise from the use of Tobacco hold a prominent place, and call loudly for reform. We pity the poor Chinese, who stupifies body and mind with opium, and the wretched Hindoo, who is under a similar slavery to his favorite plant, the Betel but we present the humiliating spectacle of an enlightened and christian nation, wasting annually more than twenty-five millions of dollars, and destroying the health and the lives of thousands, by a practice not at all less degrading than that of the Chinese or Hindoo.

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