Caret

b-Carotene (30mg/day)

Men and women

18,314

4-7 years

286 cases

(U.S.)

Retinyl palmitate (25,000IU) (2 x 2 design)

49 years of smoking

Asbestos (m = 57 years) 43 years of smoking

14,254 4,060

m = 4 years

RR = 1.36 (1.07 - 1.73) b-carotene supplement RR = 1.28 (1.04, 1.57)* b-carotene + retinyl palmitate

RR = 1.40 (0.95 - 2.07) asbestos exposed RR = 1.23 (0.96 - 1.56) heavy smokers

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