Treatment Approaches

Two treatment approaches are used:

• Fixed approach: initially 74-111 MBq (2-3 mCi) per m2 body surface area is administered with an upper limit of 185 MBq (5 mCi). This may be repeated at three monthly intervals.

• Sliding scale approach: using the sliding scale approach, a fixed dose of 111 MBq (3 mCi) is first administered. In the absence of response, a second treatment may be given after three months with a 25% increment in dose. Treatment may be repeated with continuing dose incrementation until an adequate response is obtained. The upper limit of a single treatment dose is 260 MBq (7 mCi).

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