Tin 117m Pentetate

Atkins HL, Mausner LF, Srivastava SC, et al. Tin-117 m(4+) for palliation of pain from osseous metastases: a pilot study. J Nucl Med 1995; 36:725-729. One of the early publications on tin-117 m efficacy.

Krishnamurthy GT, Swailen FM, Srivastava SC, et al. Tin-117 m(4+) DTPA: pharmacokinetics and imaging characteristics in patients with metastatic bone pain. J Nucl Med 1997; 38:230-237. Soft tissue and osseous components of biokinetics are quantitated.

Srivastava SC, Atkins HL, Krishnamurthy GT, et al. Treatment of metastatic bone pain with tin-117 m stannic diethylenetriaminepentaacetic acid. A phase I/II clinical study. Clin Cancer Res 1998; 4:61-68. Comparative dosim-etry and toxicity with other unsealed sources favor Sn-177m DPTA; good efficacy study.

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