Contraindications To Radioactive Iodine Therapy

A patient who is pregnant should not be treated with RAI (7). RAI crosses freely into the placenta, and the fetal thyroid tissue is capable of accumulating iodine after the 12th week of gestation. Administration of RAI during this period may result in severe neonatal hypothyroidism. Fetal and neonatal thyroid irradiation may also increase the risk of developing thyroid cancer later. Retained activity in the maternal bladder may also increase the risk of malignancy by direct radiation exposure...

Indications and Contraindications for 224RaCl Therapy in Ankylosing Spondylitis

The decision for treatment with 224RaCl always should be made in close collaboration of the nuclear medicine specialist and the rheumatologist. Diagnosis of AS and a failure of conservative pharmacotherapy with both nonsteroidal anti-inflammatories and analgesics, or the presence of specific contraindications against these drugs are a prerequisite. The patients frequently complain of lower back pain, severe morning stiffness in the back and spine, and of breathing impairment owing to...