HIV medication

There are four classes of medication approved by the FDA for treatment of HIV (see Charts). These are:

Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) NNRTIs bind to reverse transcriptase, a protein HIV needs to make more copies of itself. In doing so, reverse transcriptase becomes disabled. Drugs within this category include Delavirdine (Rescriptor, DLV), Efavirenz (Sustiva, EFV), and Neviapine (Viramune, NVP).

Nucleoside Reverse Transcriptase Inhibitors (NRTIs) NRTIs are faulty version reverse transcriptase. Reproduction of HIV is stalled when HIV uses NRTI instead of the normal reverse transcriptase. Drugs within this category include Abacavir (Ziagen, ABC), Abacavir, Lamivudine (Epzicom), Abacavir, Lamivudine, Zidovudine (Trizivir), Didanosine (Videx, ddI, Videx EC), Emtricitabine (Emtriva, FTC, Coviracil), Emtricitabine, Tenofovir DF (Truvada), Lamivudine (Epivir, 3TC), Lamivudine, Zidovudine (Combivir), Stavudine (Zerit, d4T), Tenofovir DF (Viread, TDF), Zalcitabine (Hivid, ddC), and Zidovudine (Retrovir, AZT, AZV).

Protease Inhibitors (PIs) PI disables protease, a protein that HIV needs to make more copies of itself. Drugs within this category include Amprenavir (Agenerase, APV), Atazanavir (Reyataz, ATV), Fosamprenavir (Lexiva, FPV), Indinavir (Crixivan, IDV), Lopinavir, Ritonavir (Kaletra, LPV/r), Nelvinavir (Viracept, NFV), Ritonavir, (Norvir, RTV), and Saquinavir (Fortovase, SQV; Invirase).

Fusion Inhibitors

Fusion Inhibitors prevent HIV from entry into cells. They include Enfuviritide (Fuzeon, T-20).

A list of drugs utilized in the treatment of HIV is provided in the Appendix. Detailed tables show doses, recommendations, expectations, side effects, contraindications, and more; available on the book's Web site (see URL in Appendix).

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