Bulk-forming laxatives are natural fibrous substances that promote large, soft stools by absorbing water into the intestines and increasing fecal bulk and peristalsis. Bulk-forming laxatives are non-absorbable. Defecation usually occurs within 8 to 24 hours but can take up to 3 days after the start of therapy for the stool to become soft and formed.

Powdered bulk-forming laxatives come in flavored and sugar-free preparations and should be mixed in a glass of water or juice, stirred. The patient should drink it immediately, followed by a half to a full glass of water. Insufficient fluid intake can cause the drug to solidify in the GI tract, resulting in intestinal obstruction. Bulk-forming laxatives do not cause dependence and may be used by patients with diverticulosis, irritable bowel syndrome, ileostomy and colostomy.

Calcium polycarbophil (FiberCon), methylcellulose (Citrucel), fiber granules (Perdiem), and psyllium hydrophilic mucilloid (Metamucil) are examples of bulk-forming laxatives. Patients with hypercalcemia should avoid calcium poly-carbophil because of the calcium in the drug. Metamucil is a nondigestible and nonabsorbent substance that when mixed with water, becomes a viscous solution. There is no protein-binding or half-life for the drug. It is excreted in the feces. There are no systemic effects. Nausea can occur with excessive use. The dry form can cause abdominal cramps.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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