Aminoglycosides Nursing Diagnosis and Collaborative Problems

Patients who receive aminoglycosides may also experience nephrotoxicty (kidney), neurotoxicity (muscle twitching, numbness or seizures), and hypersensitivity.

Here are the common nursing diagnosis related to a patient who is receiving aminoglycosides.

• Sensory-perceptual alterations: auditory ototoxicity (loss of hearing and tinnitus), vestibular ototoxicity (dizziness and loss of balance) and peripheral neuritis (tingling of the fingers and toes)

Aminoglycosides

Pregnancy Category: C

Route

Dose

Time

Amikacin (Amikin)

Protein-Binding: 4%-11%

Half-Life: 2-3 hours

IM/IV

5 mg/kg

Every 8 hours

Gentamicin (Garamycin)

Protein-Binding: Unknown

Half-Life: 2 hours

IM/IV

1-1.7 mg/kg

Infusion every 8 hours

Kanamycin (Kantrex)

Protein-Binding: 10%

Half-Life: 2-3 hours

Pregnancy Category: D

IM

3.75 mg/kg

Every 6 hours

Neomycin SO4 (Myclfradin)

Protein-Binding: 10%

Half-Life: 2-3 hours

PO (GI Surgery)

1 g

Every hour for 4 doses

1 g

Every 4 hours there-

after for 24 hours or

other regimens

(Hepatic Coma)

4-12 g/d

Divided doses

IM

15mg/kg/d

Every 6 h for 4 doses

Max 1 g/d

Netilmicin (Netromycin)

Protein-Binding: 10%

Half-Life: 2-3 hours

Pregnancy Category: D

IM/IV

1.3-2.2 mg/kg

Every 8 hours

Aminoglycosides (continued)

Pregnancy Category: C

Streptomycin S O4

Protein-Binding: 30%

Half-Life: 2-3 hours

Route

Dose

Time

IM (tuberculosis)

1 gm

Every day with

antimycobacterials

(Endocarditis)

1 g

Every 12 hours for

1 week. Dose may

be decreased

Tobramycin SO4

(Nebcin)

Protein-Binding: 10%

Half-Life: 2-3 hours

IM/IV

0.75 mg to

Every 6 hours

1.25 mg/kg

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