Biologic products such as vaccines do not undergo the pharmacokinetic process that is associated with other drug therapies. Vaccines are generally safe. Some common mild reactions include swelling at the injection site and fever. Absolute contraindications for the use of vaccines include anaphylactic reaction to a specific vaccine or component of another vaccine or moderate or severe illness.
Healthcare providers are expected to report vaccine adverse events to public health officials who report these to the CDC every week using the Vaccine Adverse Events Reporting System (VAERS), which is used to provide compensation for injury and death caused by vaccination.
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