▲ FIGURE 6-17 The repeating disaccharides of glycosaminoglycans (GAGs), the polysaccharide components of proteoglycans. Each of the four classes of GAGs is formed by polymerization of monomer units into repeats of a particular disaccharide and subsequent modifications, including addition of sulfate groups and inversion (epimerization) of the carboxyl group on carbon 5 of d-glucuronic acid to yield l-iduronic acid. Heparin is generated by hypersulfation of heparan sulfate, whereas hyaluronan is unsulfated. The number (n) of disaccharides typically found in each glycosaminoglycan chain is given. The squiggly lines represent covalent bonds that are oriented either above (d-glucuronic acid) or below (l-iduronic acid) the ring.
Was this article helpful?
Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.